My team interest is developing fast and accurate AI models, algorithms, distributed computing platforms, and databases for bioinformatics in personalized medicine, drug design, and virtual screening, as well as developing big-data algorithms, analysis tools, databases, and web portals. In 2010, I obtained my Ph.D. in Bioinformatics from the computational biology department at USC, co-advised by Michael Waterman and Magnus Nordborg. My main expertise is in statistics, algorithms, machine learning, and population genetics.
Previously at Illumina Inc., I was the main developer behind the BaseSpace App, MethylSeq, which is the bioinformatics cloud software to detect methylated cytosines in DNA from bisulfite treated next-gen sequencing data. I was also the lead bioinformatician in inter-disciplinary company projects involving cancer, forensics, exome, whole-genome sequencing. I did a three-and-a-half-year PostDoc with Prof. Nelson Freimer at Human Genetics, UCLA (Nov 2010-Mar 2014), working on population genetics and trait mapping (pedigree or population) in vervet monkeys, analyzing the whole-genome DNA sequences from >700 monkeys of a vervet pedigree and >100 wild population monkeys. In Oct 2010, I completed my PhD in Computational Biology and Bioinformatics at USC, working primarily on association mapping and population genetics of Arabidopsis thaliana, under the supervision of Magnus Nordborg. Before pursuing my PhD under Magnus, I had worked on the topic of gene function/network inference from gene expression data through graph theory. In July 2003, I received B.S. of Biology from Fudan University. During my undergraduate, with lots of free time on hand (as expected for a college student), I learnt C/C++, PostgreSQL DB, Python, and Linux network administrations on the side. I have been fascinated with computers ever since I played with an Intel-8088 PC in my 8th grade.
Email: polyactis at gmail.com
2003.08 - 2010.10 University of Southern California, Los Angeles, Ph.D. in Bioinformatics
1999.09 - 2003.07 Fudan University, Shanghai, B.S. in Biological Sciences
1996.09 - 1999.07 Shanghai Chuansha Senior High School
2022.01 - Senior Director of Bioinformatics, Genecast Corp Ltd.
2015.05 - (on leave) Professor, PI, Director of Bioinformatics, Shanghai Institute of Material Medica
2014.04 - 2015.05 Bioinformatics Scientist, Illumina Inc. San Diego
2010.11 - 2014.04 PostDoc, University of California Los Angeles
Awards & Honours