CV

Senior Director of Bioinformatics

• AI model for MCED (Multi Cancer Early Detection) https://www.genecast.com.cn/solutions/detail?id=29 (Bie et al. Nature Communications).
• Optimize core bioinformatics algorithms using deep learning, machine learning techniques.
• Statiscal models for MRD (Minimal Residual Disease) fixed-panel and WES custom-panel products.
• Teach Bayesian Statistics, Machine/Deep Learning, Julia/Rust Programming.
• AI computing platform.

Professor/Principal Investigator, Director of Bioinformatics

• Develop AI models and algorithms in personalized medicine (target discovery, validation, biomarker) and AI models in drug design and virtual screening.
• Establish the AI computing platform.
• Accucopy _ a computational method that infers Allele-specific Copy Number alterations from low-coverage low-purity tumor sequencing Data.
• Teach Chris Bishop 2006 book "Pattern Recognition and Machine Learning".
• Teach Julia programming language, Matrix Computing, Optimization.

Bioinformatics Scientist

• MethylSeq BaseSpace app (in C#).
• UFlow a Directed-Acyclic-Graph Workflow system in C# that boosts Illumina bioinformatics workflow runtime by >50X.
• Bioinformatics libraries in GOlang that sped up the analysis by >100X.
• Forensics, cancer, whole-genome, exome competitive analyses.

PhD in Computational Biology and Bioinformatics

B.S. in Biology

Accucopy

• A computational method that infers Allele-specific Copy Number alterations from low-coverage low-purity tumor sequencing Data.

eGADA

• enhanced GADA: a fast segmentation algorithm utilizing the Sparse Bayesian Learning (or Relevance Vector Machine). It can be applied to array intensity data, NGS sequencing data, or any sequential data that displays characteristics of stepwise functions. Enhancements include: 1) a customized Red-Black tree to significantly expedite the final backward elimination step; 2) coded in C++, which is better structured than C; 3) export eGADA.so, a Python API.

• 江苏省省双创人才

• China Thousand-Talent Program

• Hundred-Talent Program of Chinese Academy of Sciences

• Merit Award Fellowship, University of Southern California.

• Third Award, Computer Programming Contest, Fudan University.

• People's Scholarship, Fudan University.

• Third Award, National High School Mathematics Competition of China.

• Third Award, Junior High School Physics Competition, Shanghai.